My research examines air pollution exposure experienced by children during commutes between their home and their school in the Greater Toronto Area (GTA). Toronto is a major North American city; whose large population and high traffic volume make it an ideal location for air pollution studies. By applying a Geographic Information System (GIS) based approach to air pollution modelling known as Land-Use Regression, ambient pollution concentration estimates are developed on spatially precise scales. By simulating commute routes on along Toronto’s road and cycling network we examine variations in exposure attributed to commute timing, vehicle used, and route taken. My research examined how route optimization solutions can be used to mitigate air pollution dosage during the commute and have the potential to reduce health burdening of air-pollution related respiratory effects.